SONICC
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Overview
SONICC, the Second Order Non-linear Imaging of Chiral Crystals, uses a femtosecond pulsed laser to exploit the frequency-doubling effect found in the vast majority of protein crystals and produces high-contrast images with negligable background signal.
Applications:
- Protein Crystallization
- Active Pharmaceutical Ingredients (APIs)
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Fast :
Quickly find difficult to see crystals simply by glancing at thumbnails.
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Solve :
Determine additional conditions for optimization.
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Identify :
Even sub-micron crystals buried in precipitate can be found by SONICC.
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Define :
Definitively distinguish between precipitate and crystals.
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API :
Measure API crystallinity well below 0.1%.
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Versitile :
SONICC is available as an upgrade to the Rock Imager 1000 or as a benchtop system that includes visible light optics.